Research articles

AR Chandrasekaran, M MacIsaac, P Dey, O Levchenko, L Zhou, M Andres, BK Dey & K Halvorsen, Cellular microRNA detection with miRacles: microRNA activated conditional looping of engineered switches. Sci. Adv. DOI: 10.1126/sciadv.aau9443 (2018). [PDF]

AR Chandrasekaran* & K Halvorsen, Controlled disassembly of a DNA tetrahedron using strand displacement. Nanoscale Adv. DOI: 10.1039/C8NA00340H (2018). [PDF

M Xiao, AR Chandrasekaran, W Ji, F Li, T Man, C Zhu, X Shen, H Pei, Q Li & L Li, Affinity-modulated molecular beacons on MoS2 nanosheets for microRNA detection. ACS Appl. Mater. Interfaces 10: 35794-35800 (2018). [PDF]

AR Chandrasekaran,* Reconfigurable DNA nanoswitches for graphical readout of molecular signals. ChemBioChem 19: 1018-1021 (2018). [PDF]

AR Chandrasekaran,* O Levchenko, D Patel, M MacIsaac & K Halvorsen, Addressable configurations of DNA nanostructures for rewritable memory. Nucleic Acids Res. 45: 11459-11465 (2017). [PDF]

C Hernandez, JJ Birktoft, YP Ohayon, AR Chandrasekaran, H Abdallah, R Sha, V Stojanoff, C Mao & NC Seeman, Self-assembly of 3D DNA crystals containing a torsionally stressed component. Cell Chem. Biol. 24, 1401-1406 (2017). [PDF]

K Halvorsen, M Kizer, X Wang, AR Chandrasekaran & M Basanta-Sanchez, Shear dependent LC purification of an engineered  DNA nanoswitch and implications for DNA origami. Anal. Chem. 89: 5673-5677 (2017). [PDF]

V Valsangkar, AR Chandrasekaran,# R Wang, P Haruehanroengra, O Levchenko, K Halvorsen & J Sheng, Click-based functionalization of a 2'-O-propargyl-modified branched DNA nanostructure. J. Mater. Chem. B, 5: 2074-2077 (2017). [PDF]

HO Abdallah, YP Ohayon, AR Chandrasekaran, R Sha, KR Fox, T Brown, DA Rusling, C Mao & NC Seeman, Stabilisation of self-assembled DNA crystals by triplex-directed photo-cross-linking. Chem. Comm. 52: 8014-8017 (2016). [PDF]

AR Chandrasekaran, J Zavala & K Halvorsen, Programmable DNA nanoswitches for detection of nucleic acid sequences. ACS Sens. 1: 120-123 (2016). [PDF]

YP Ohayon, R Sha, O Flint, W Liu, B Chakraborty, HKK Subramanian, J Zheng, AR Chandrasekaran, H Abdallah, X Wang, X Zhang & NC Seeman, Covalent linkage of one-dimensional DNA arrays bonded by paranemic cohesion. ACS Nano 9: 10304-10312 (2015). [PDF]

YP Ohayon, R Sha, O Flint, AR Chandrasekaran, H Abdallah, T Wang, X Wang, X Zhang & NC Seeman, Topological linkage of DNA tiles bonded by paranemic cohesion. ACS Nano 9: 10296-10303 (2015). [PDF]

 J Zhao, AR Chandrasekaran, Q Li, X Li, R Sha, NC Seeman & C Mao, Post-assembly stabilization of rationally designed DNA crystals. Angew. Chem. Int. Ed. 54: 9936-9939 (2015). [PDF]

DA Rusling, AR Chandrasekaran,# YP Ohayon, T Brown, KR Fox, R Sha, C Mao & NC Seeman, Functionalizing designer DNA crystals with a triple-helical veneer. Angew. Chem. Int. Ed. 53: 3979-3982 (2014). [PDF]

R Sha, JJ Birktoft, N Nguyen, AR Chandrasekaran, J Zheng, X Zhao, C Mao & NC Seeman, Self-assembled DNA crystals: The impact on resolution of 5'-phosphates and the DNA source. Nano Lett. 13: 793-797 (2013). [PDF]

PK Mandal, AR Chandrasekaran, BR Madhanagopal, S Venkadesh & N Gautham, Ring crystals of oligonucleotides: Growth stages and X-ray diffraction studies. J. Cryst. Growth 354: 20-26 (2012). [PDF]

AR Chandrasekaran, JR Venugopal, S Sundarrajan & S Ramakrishna, Fabrication of a nanofibrous scaffold with improved bioactivity for culture of human dermal fibroblasts for skin regeneration. Biomed. Mater. 6: 015001 (2011). [PDF]

ReviewS & Commentaries

BR Madhanagopal, S Zhang, E Demirel, H Wady and AR Chandrasekaran,* DNA nanocarriers: Programmed to deliver. Trends Biochem. Sci. 43: 997-1013 (2018). [PDF]

X Wang,* AR Chandrasekaran,#* Z Shen, YP Ohayon, T Wang, ME Kizer, R Sha, C Mao, H Yan, X Zhang, S Liao, B Ding, B Chakraborty, N Jonoska, D Niu, H Gu, J Chao, X Gao, Y Li, T Ciengshin and NC Seeman, Paranemic crossover DNA: There and back again. Chem. Rev. DOI: 10.1021/acs.chemrev.8b00207 (2018). [PDF]

PL Xavier and AR Chandrasekaran,* DNA-based construction at the nanoscale: emerging trends and applications. Nanotechnology 29: 062001 (2018). [PDF]

AR Chandrasekaran and DA Rusling, Triplex-forming oligonucleotides: A third strand for DNA nanotechnology. Nucleic Acids Res. 46: 1021-1037 (2017). [PDF]

AR Chandrasekaran, DNA arrays with a silver lining. ChemBioChem 18: 1886-1887 (2017). [PDF]

AR Chandrasekaran* and O Levchenko, DNA nanocages. Chem. Mater. 28: 5569-5581 (2016). [PDF]

AR Chandrasekaran,* H Wady and HKK Subramanian,* Nucleic acid nanostructures for chemical and biological sensing. Small 12: 2689-2700 (2016). [PDF]

AR Chandrasekaran,* N Anderson, M Kizer, K Halvorsen and X Wang,* Beyond the fold: Emerging biological applications of DNA origami. ChemBioChem 17: 1081-1089 (2016). [PDF]

AR Chandrasekaran, DNA‐nanoparticle tinkertoys. ChemBioChem 17: 1090-1092 (2016). [PDF]

AR Chandrasekaran* & R Zhuo, A ‘tile’ tale: Hierarchical self-assembly of DNA lattices. Appl. Mat. Today 2: 7-16 (2016). [PDF]

AR Chandrasekaran,* Programmable DNA scaffolds for spatially-ordered protein assembly. Nanoscale 8: 4436-4446 (2016). [PDF]

AR Chandrasekaran,* DNA origami and biotechnology applications: A perspective. J. Chem. Technol. Biotechnol. 91: 843-846 (2016). [PDF]

S Sundarrajan, AR Chandrasekaran and S Ramakrishna, An update on nanomaterials‐based textiles for protection and decontamination. J. Am. Cer. Soc. 93: 3955-3975 (2010). [PDF]