Research articles in DNA nanotechnology



A DNA rotary nanodevice operated by enzyme-initiated strand resetting.

AR Chandrasekaran*
Chem. Commun. 60: 534 (2024). [PDF]

Unusual structural properties of switchback DNA.

BR Madhanagopal, H Talbot, A Rodriguez, JM Louis, H Zeghal, S Vangaveti, K Reddy & AR Chandrasekaran*
bioRxiv, 2023.11.15.563609 (2023). [PDF]

Self-assembly of DNA nanostructures in different cations.

A Rodriguez, D Gandavadi, J Mathivanan, T Song, BR Madhanagopal, H Talbot, J Sheng, X Wang*AR Chandrasekaran*
Small, 19: 2300040 (2023). [PDF]

Fluorometric determination of DNA nanostructure biostability.

H Talbot, BR Madhanagopal, A Hayden, K Halvorsen & AR Chandrasekaran*
ACS Applied Bio Materials, 6: 3074 (2023). [PDF]

Caffeine-induced release of small molecules from DNA nanostructures.

BR Madhanagopal, S Chen, CD Platt & AR Chandrasekaran*
iScience, 26: 106564 (2023). [PDF]

The role of size in biostability of DNA tetrahedra.

J Vilcapoma, A Patel, AR Chandrasekaran* & Ken Halvorsen*
Chemical Communications, 59: 5083 (2023). [PDF]

Toehold clipping: A mechanism for remote control of DNA strand displacement.

H Faheem, J Mathivanan, H Talbot, H Zeghal, S Vangaveti, J Sheng, AA Chen & AR Chandrasekaran*
Nucleic Acids Research, 51: 4055 (2023). [PDF]

Encoding, decoding, and rendering information in DNA nanoswitch libraries.

H Talbot, K Halvorsen & AR Chandrasekaran*
ACS Synthetic Biology, 12: 978 (2023). [PDF]

High-throughput single-molecule quantification of individual base stacking energies in nucleic acids.

JA Punnoose, KJ Thomas, AR Chandrasekaran, J Vilcapoma, A Hayden, T Banco & K Halvorsen
Nature Communications, 14: 631 (2023). [PDF]

Sequence-selective purification of biological RNAs using DNA nanoswitches.

L Zhou, A Hayden, AR Chandrasekaran, J Vilcapoma, C Cavaliere, P Dey, S Mao, J Sheng, BK Dey, P Rangan & K Halvorsen
Cell Reports Methods, 1: 100126 (2021). [PDF]

A mini DNA-RNA hybrid origami nanobrick.

L Zhou, AR Chandrasekaran, M Yan, VA Valsangkar, JI Feldblyum, J Sheng & K Halvorsen
Nanoscale Advances, 3: 4048 (2021). [PDF]

Orthogonal control of DNA nanoswitches with mixed physical and biochemical cues.

NT Forrest, J Vilcapoma, K Alejos, K Halvorsen* & AR Chandrasekaran*
Biochemistry, 60: 250 (2021). [PDF]

Hybrid DNA/RNA nanostructures with 2′-5′ linkages.

AR Chandrasekaran,*  J Mathivanan, P Ebrahimi, J Vilcapoma, AA Chen, K Halvorsen & J Sheng*
Nanoscale, 12: 21583 (2020). [PDF]

Ribonuclease-responsive DNA nanoswitches.

AR Chandrasekaran,* R Trivedi & K Halvorsen*
Cell Reports Physical Sciences, 1: 100117 (2020). [PDF]

Exceptional nuclease resistance of paranemic crossover (PX) DNA and crossover-dependent biostability of DNA motifs.

AR Chandrasekaran,* J Vilcapoma, P Dey, SW Wong-Deyrup, BK Dey & K Halvorsen*
Journal of the American Chemical Society (JACS), 142: 6814 (2020). [PDF]

Click and photo-release dual-functional nucleic acid nanostructures.

VA Valsangkar, AR Chandrasekaran,* L Zhou, S Mao, GW Lee, M Kizer, X Wang, K Halvorsen & J Sheng*
Chemical Communications, 55: 9709 (2019). [PDF]

Integration of a photocleavable element into DNA nanoswitches.

AR Chandrasekaran,* JA Punnoose, V Valsangkar, J Sheng & K Halvorsen*
Chemical Communications, 55: 6587 (2019). [PDF

Controlled disassembly of a DNA tetrahedron using strand displacement.

AR Chandrasekaran* & K Halvorsen*
Nanoscale Advances, 1: 969 (2019). [PDF

Reconfigurable DNA nanoswitches for graphical readout of molecular signals.

AR Chandrasekaran*
ChemBioChem 19: 1018 (2018). [PDF]

Addressable configurations of DNA nanostructures for rewritable memory.

AR Chandrasekaran,* O Levchenko, D Patel, M MacIsaac & K Halvorsen*
Nucleic Acids Research, 45: 11459 (2017). [PDF]

Shear dependent LC purification of an engineered  DNA nanoswitch and implications for DNA origami.

K Halvorsen, M Kizer, X Wang, AR Chandrasekaran & M Basanta-Sanchez
Analytical Chemistry, 89: 5673 (2017). [PDF]

Click-based functionalization of a 2'-O-propargyl-modified branched DNA nanostructure.

V Valsangkar, AR Chandrasekaran,^ R Wang, P Haruehanroengra, O Levchenko, K Halvorsen & J Sheng
Journal of Materials Chemistry B, 5: 2074 (2017). [PDF]

Covalent linkage of one-dimensional DNA arrays bonded by paranemic cohesion.

YP Ohayon, R Sha, O Flint, W Liu, B Chakraborty, HKK Subramanian, J Zheng, AR Chandrasekaran, H Abdallah, X Wang, X Zhang & NC Seeman
ACS Nano 9: 10304 (2015). [PDF]

Topological linkage of DNA tiles bonded by paranemic cohesion.

YP Ohayon, R Sha, O Flint, AR Chandrasekaran, H Abdallah, T Wang, X Wang, X Zhang & NC Seeman
ACS Nano 9: 10296 (2015). [PDF]